Skip links

Author: oncologs.com

abt199/venetoclax-synergism-with-thiotepa-in-acute-myeloid-leukemia-(aml)-cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

“[…] the combination of ABT199/venetoclax and Thio enhances the cytotoxicity of (Flu+Clad+Bu) in AML cell lines and leukemia patient-derived cell samples.” Credit: 2024 Valdez et al. “[…] the combination of ABT199/venetoclax and Thio enhances the cytotoxicity of (Flu+Clad+Bu) in AML cell lines and leukemia patient-derived
colorectal-cancer-gene-implicated-in-broad-range-of-solid-tumors

Colorectal cancer gene implicated in broad range of solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and
a-new-path-to-drug-diversity

A new path to drug diversity

Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products from Bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By exploring protein evolution, a team led by Helge
morality-among-low-risk-differentiated-thyroid-cancer-survivors-in-the-us.

Morality among low-risk differentiated thyroid cancer survivors in the U.S.

A new study has shown that overall and cause-specific mortality rates in individuals in the U.S. with low-risk differentiated thyroid cancer (DTC) are low. The study is published in the peer-reviewed journal Thyroid®, the official journal of the American Thyroid Association® (ATA®). Click here to read the article now. Credit: Mary Ann
new-bioinformatics-tool-to-identify-chromosomal-alterations-in-tumour-cells

New bioinformatics tool to identify chromosomal alterations in tumour cells

A team of the University of Barcelona (UB) and the Biomedical Research Institute of Barcelona (IRB Barcelona) has designed a new bioinformatics tool to identify the chromosomal alterations that are characteristic of cancer cells. This new detection system, known as QATS (QuAntification of Toroidal nuclei
scientists-find-core-regulatory-circuit-controlling-identity-of-aggressive-leukemia

Scientists find core regulatory circuit controlling identity of aggressive leukemia

A collaboration between scientists from St. Jude Children’s Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer. These proteins comprise a core regulatory circuit (CRC) that surprisingly incorporates a dysregulated signaling protein.
revolutionizing-gastric-cancer-treatment-through-personalized-3d-bioprinting

Revolutionizing gastric cancer treatment through personalized 3D bioprinting

Gastric cancer ranks among the most widespread diseases in Asian populations, with South Koreans experiencing the third-highest incidence globally in 2020, as reported by the International Agency for Research on Cancer. Recently, a collaborative research effort between Pohang University of Science and Technology (POSTECH) and
Explore
Drag