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Key discovery by Duke-NUS advances fight to reduce breast cancer recurrence

Singapore, 26 August 2024 — In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in oestrogen receptor-positive (ER+) breast cancer, this protein acts

Unraveling the role of CDCA7 in maintenance of DNA methylation

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism. Disruptions in the standard DNA methylation patterns can lead to immunodeficiency and diseases such as cancer. Helicase lymphoid-specific

Old chemo drug, new pancreatic cancer therapy?

The fight against cancer is an arms race, and one of the most effective weapons in clinicians’ arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer. However, the Nobel Prize-winning strategy is ineffective for most pancreatic ductal adenocarcinoma

When is the best time of day for cancer treatment?

How effective medications are depends on various factors, including the time of day when they are administered. Why? Because our bodies don’t always function exactly the same. Instead, they follow the cycle set by their internal clock, otherwise known as circadian rhythm. But since each
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