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A computational model built by researchers at the Institute of Research in Biomedicine (IRB Barcelona) and the Centre for Genomic Regulation (CRG) can predict which drugs will be most effective in treating diseases caused by mutations that can bring protein synthesis to a halt, resulting

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.   Credit: A/Prof Steven Zuryn University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.   Dr Anne Hahn and Associate Professor Steven

Reston, VA (August 20, 2024) —A new molecular imaging technique that pairs a novel tracer with a next-generation PET/CT scanner can identify neuroblastoma in children with high sensitivity, requiring a scan time of only minutes and no sedation or anesthesia. With its ability to accurately

“[…] there is strong preclinical evidence that disruption of NKG2A interactions with HLA-E can stimulate both NK cell and cytotoxic T cell effector functions against cancer.” Credit: Fisher et al. “[…] there is strong preclinical evidence that disruption of NKG2A interactions with HLA-E can stimulate

(MEMPHIS, Tenn. – August 20, 2024) Children who survive a brain tumor often experience effects from both the cancer and its treatment long after therapy concludes. Scientists at St. Jude Children’s Research Hospital found very young children treated for brain tumors were less prepared for

Epigenetics, the modification of chromosomes without altering DNA sequences, serves as a crucial regulatory mechanism for gene expression. Among the various epigenetic marks, N6-methyladenosine (m6A) modifications on RNA have gained significant attention in recent years for their role in various biological processes, including cancer development

Hepatocellular carcinoma (HCC) poses a substantial health burden globally, with liver cancer being the fourth most common cause of cancer-related mortality worldwide. In China, where the incidence of HCC is particularly high due to the prevalence of chronic hepatitis B virus (HBV) infection, the disease

Esophageal cancer, a highly aggressive malignancy originating in the esophageal epithelium, poses significant public health challenges in China, where it ranks sixth in incidence and fifth in mortality among cancers. The country’s large population contributes to over half of the global cases and deaths from

Osaka, Japan – Pancreatic cancer is an aggressive disease with few available treatments. Thankfully, researchers are hard at work to improve treatment options, and researchers from Japan have now unveiled something promising. In a study published this month in Cancer Science, researchers from Osaka University

HCV infection is the underlying cause for chronic Hepatitis C (CHC), liver cirrhosis, and liver cancer or hepatocellular carcinoma (HCC). In 2019, over 2,90,000 people died of HCV-related diseases. Recent medical advancement made a new breakthrough treatment available for patients with hepatitis C. DAAs that