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The rise in the incidence of oropharyngeal squamous cell carcinomas (OPSCCs) linked to human papillomavirus (HPV)-16 infection has become notable, surpassing cervical high-risk HPV infections by 2019. HPV-associated OPSCCs present a better prognosis compared to traditional oropharyngeal malignancies, largely due to lower correlations with chronic

Cancers of the digestive system mainly include esophageal, gastric, liver, gallbladder, pancreatic, and colorectal cancers. With an estimated 20 million new cases, colorectal cancer is the third most common cancer and the second leading cause of cancer-related deaths. Closely followed by gastric and liver cancers,

Natasha Sheybani, assistant professor of biomedical engineering at the University of Virginia School of Engineering, will collaborate with researchers at Children’s National Hospital to study the combination of two therapies for pediatric brain cancer.  Credit: UVA Engineering Natasha Sheybani, assistant professor of biomedical engineering at

Oral Leukoplakia (OLK) is recognized as a predominant potentially malignant oral epithelial lesion (PMOEL), posing significant risks due to its potential progression to oral squamous cell carcinoma (OSCC). OSCC, a major subset of head and neck cancers, accounts for a significant global health burden, especially

“Herein we discuss how gut microbiota and microbial metabolites regulate basal inflammation levels in the gut and the healing process of the bowel after surgery.” Credit: 2024 Hajjar et al. “Herein we discuss how gut microbiota and microbial metabolites regulate basal inflammation levels in the

SAN ANTONIO — August 19, 2024 —Southwest Research Institute (SwRI) has developed a unique technology to screen new DNA-targeting therapeutics designed to treat cancer and other diseases. Combining SwRI’s 3D drug screening software tool and machine learning techniques, SwRI scientists successfully predicted the DNA binding

Lung cancer has high morbidity and mortality rates worldwide. It is characterized by rapid progression, poor prognosis, and susceptibility to chemotherapy. The most common route of metastasis in lung cancer is through mediastinal lymph nodes (MLN), which significantly affects the stage and prognosis of the

New York, NY [August 16, 2024]—Scientists at the Icahn School of Medicine at Mount Sinai have identified a new class of RNAs packed into tiny particles known as extracellular vesicles (EVs) that could revolutionize how cancer and other diseases are diagnosed. The team found that

This paper, led by Professor Wu (Wenzhou Institute University, Wenzhou Medical University) and Professor Huang (Northeastern University), explores LLPS, a phenomenon closely associated with various diseases, including cancer and neurodegenerative disorders. As a frontier research area, LLPS plays a significant role in cancer through its

Corn, a staple food crop consumed by billions of people and animals worldwide, is frequently contaminated by the fungal toxin aflatoxin B1, a highly potent carcinogen produced by the fungus Aspergillus flavus. Credit: The Biodesign Institute at Arizona State University Corn, a staple food crop