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Nanobody inhibits metastasis of breast tumor cells to lung in mice

“In the present study we describe the development of an inhibitory nanobody directed against an extracellular epitope present in the native V-ATPase c subunit.” Credit: 2024 Li et al. “In the present study we describe the development of an inhibitory nanobody directed against an extracellular

A call to bridge the cancer care – chronic illness management gap

Providing cancer care for someone who also has a chronic illness, such as diabetes or high blood pressure, requires a systematic, co-management approach to produce better cancer and overall health outcomes, said UNC Lineberger Comprehensive Cancer Center’s Samuel Cykert, MD. Credit: UNC Lineberger Comprehensive Cancer

New mechanism of action kills cancer cells

The research was carried out in Dr. Johannes Karges’ Medicinal Inorganic Chemistry group in collaboration with doctoral student Nicolás Montesdeoca and two Bachelor students, Lukas Johannknecht and Elizaveta Efanova, and with the support of Dr. Jaqueline Heinen-Weiler from the Medical Imaging Center at Ruhr University

Response of BRAF-mutated spindle cell sarcoma to BRAF/MEK inhibitors

“This is the first report of spindle cell sarcoma BRAF V600E/S607T double-mutated, responding to a combination of B-Raf and MEK inhibitors.” Credit: 2024 Sinichenkova et al. “This is the first report of spindle cell sarcoma BRAF V600E/S607T double-mutated, responding to a combination of B-Raf and

Histopathologic features and differential diagnosis in challenging cases of nodular lymphocyte predominant B-cell lymphoma/Nodular Lymphocyte Predominant Hodgkin Lymphoma

This review offers an in-depth exploration of Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL), highlighting its distinct characteristics across various domains such as epidemiology, clinical presentation, histopathology, immunophenotype, genetic findings, and challenges in differential diagnosis. Credit: Elaine S. Jaffe, Yanna Ding This review offers an in-depth
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