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Today, about 25% of drugs approved to treat cancer are derived from nature – from the bark of a tree to marine life to bacteria in the soil. However, great potential remains in the discovery of natural products with properties that can prevent cancer or

“In our study, we postulated that these differences were driven by three common low-risk (LR) missense variants: p.I157T, p.S428F, and p.T476M, all of which have a BC odds ratio of

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism. Disruptions in the standard DNA methylation patterns can lead to immunodeficiency and diseases such as cancer. Helicase lymphoid-specific

The fight against cancer is an arms race, and one of the most effective weapons in clinicians’ arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer. However, the Nobel Prize-winning strategy is ineffective for most pancreatic ductal adenocarcinoma

Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest. Austocystin D promotes cell

HOUSTON – (Aug. 23, 2024) – The lotus leaf is a pioneer of self-cleaning, water-repellant engineering. Water droplets all but hover on its surface, whose unique texture traps air in its nanosized ridges and folds. Credit: (Photo by Gustavo Raskosky) HOUSTON – (Aug. 23, 2024)

COLUMBUS, Ohio – Nearly half of counties in the United States have at least one ‘pharmacy desert’ where there is no retail pharmacy within 10 miles, according to a new study published by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G.

“For the first time, we are revealing that advanced cancer tissue with elevated SULT1E1-protein may reactivate in a reducing-state initiated by chalcone, but remain dormant in an oxidative environment.“ Credit: Nazmeen et al. “For the first time, we are revealing that advanced cancer tissue with

How effective medications are depends on various factors, including the time of day when they are administered. Why? Because our bodies don’t always function exactly the same. Instead, they follow the cycle set by their internal clock, otherwise known as circadian rhythm. But since each

Recent research highlights the importance of targeted therapies for treating advanced colorectal cancer (CRC) with rare genetic variants. These mutations, often linked to poor prognosis and limited response to conventional treatments, are being addressed through advanced sequencing technologies and new targeted drugs. This study explores