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Researchers discover cell ‘crosstalk’ that triggers cancer cachexia

New research from the University of Oklahoma reveals a previously unknown chain of events sparking the development of cancer cachexia, a debilitating muscle-wasting condition that almost always occurs in people diagnosed with pancreatic cancer. Credit: University of Oklahoma New research from the University of Oklahoma
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Melanomas resist drugs by ‘breaking’ genes

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target
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Softer tumours fuel more aggressive spread of triple-negative breast cancer

A metabolic ‘survival switch’ controlled by the stiffness of triple-negative breast tumours can significantly influence how successfully their cancerous cells spread to other organs, according to new findings from the Garvan Institute of Medical Research. Credit: Dr Elysse Filipe / Garvan Institute Softer tumours fuel
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Study lays the basis for new knowledge on gastrointestinal diseases

The meeting point of the stomach and esophagus, the so-called gastro-esophageal junction, is a region of the human body that is not well-suited to the modern lifestyle. Stress, alcohol, nicotine and severe obesity are often triggers for pathological changes to the mucosal membrane in this
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Next-gen lab chip transforms cancer detection: triple-threat cell sorting unveiled

Researchers have unveiled a microfluidic device that significantly improves the separation of tumor cells and clusters from malignant effusions. This novel technology promises to advance the diagnosis and treatment monitoring of cancer by enabling the high-throughput, continuous-flow ternary separation of single tumor cells, tumor cell
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