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iron-restriction-keeps-blood-stem-cells-young

Iron restriction keeps blood stem cells young

March 8, 2024—BRONX, NY—As we age, our hematopoietic (blood-forming) stem cells (HSCs) become less able to produce new red and white blood cells and other vital blood components—contributing to chronic inflammation and accelerating the onset of blood cancers and degenerative diseases. Researchers at Albert Einstein
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New insights into the growth and spread of cancer cells

Cancer cells are characterized by their aggressiveness: they grow rapidly and spread to other parts of the body. To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates certain genes on the cancer cell’s DNA strand,
a-step-towards-clinic-ready-patient-derived-organoids

A step towards clinic-ready patient-derived organoids

LA JOLLA (March 6, 2024)—Pancreatic cancer has the highest mortality rate of all major cancers and is projected to become the second-leading cause of cancer-related deaths in the United States by 2030. It is especially difficult to treat because pancreatic tumors grow so quickly and
gz17-6.02-with-proteasome-inhibitors-kills-multiple-myeloma-cells

GZ17-6.02 with proteasome inhibitors kills multiple myeloma cells

“We believe that developing GZ17-6.02 as a novel multiple myeloma agent potentially opens up a multitude of novel opportunities to develop therapeutic approaches which will prolong patient survival.” Credit: 2024 Booth et al. “We believe that developing GZ17-6.02 as a novel multiple myeloma agent potentially
nanosurgical-tool-could-be-key-to-cancer-breakthrough

Nanosurgical tool could be key to cancer breakthrough

The high-tech double-barrel nanopipette, developed by University of Leeds scientists, and applied to the global medical challenge of cancer, has – for the first time – enabled researchers to see how individual living cancer cells react to treatment and change over time – providing vital
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