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“Given that the MET inhibitor capmatinib caused a remarkable response in Dr. Blagosklonny, a pertinent question remains as to why he was not treated with ‘preemptive drug combinations’ […]” Credit: 2024 Dent. “Given that the MET inhibitor capmatinib caused a remarkable response in Dr. Blagosklonny,

Physicians and scientists have known for many years that our genetics not only shape our physical features like our smiles but also our risk for developing certain diseases. Credit: Medical University of South Carolina Physicians and scientists have known for many years that our genetics

Lung cancer is not the most common form of cancer, but it is by far the deadliest. Credit: Photo courtesy the University of Texas at Arlington Lung cancer is not the most common form of cancer, but it is by far the deadliest. Despite treatments

Vitamin B6 is beneficial in many ways, notably for its role in maintaining a strong immune system. However, when pancreatic cancer develops, its cells also need vitamin B6 to replicate. During the ensuing tug of war over a limited supply of vitamin B6, pancreatic cancer

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes. Transcriptional regulation, a prevalent type for regulating gene expression, involves the control of target genes

New York, NY (February 22, 2024)—Recent developments in cancer research have highlighted the vital role of the immune system, particularly in the notable successes of cancer immunotherapy. Credit: Krishna, et al., Science New York, NY (February 22, 2024)—Recent developments in cancer research have highlighted the

The Mark Foundation for Cancer Research has once again teamed up with Gabrielle’s Angel Foundation for Cancer Research to fund two new collaborative grants totaling $1M. These grants were made available exclusively to current and former Gabrielle’s Angels grantees. The two outstanding scientific teams below

Scientists at the Scripps Research Institute and the Evolutionary Venomics Lab (EVL) at the Centre for Ecological Sciences (CES), Indian Institute of Science (IISc) have developed a synthetic human antibody that can neutralise a potent neurotoxin produced by the Elapidae family of highly toxic snakes,

The FAST-Forward randomized trial from the UK found that ultrahypofractionated whole breast irradiation (WBI, 26 Gy in five fractions over 1 week) was just as effective as the 3-week regimen for local control. This approach can reduce treatment time from 3−5 weeks to 1 week,

Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care. Credit: Egeblad lab/Cold