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“In the present study we describe the development of an inhibitory nanobody directed against an extracellular epitope present in the native V-ATPase c subunit.” Credit: 2024 Li et al. “In the present study we describe the development of an inhibitory nanobody directed against an extracellular

Providing cancer care for someone who also has a chronic illness, such as diabetes or high blood pressure, requires a systematic, co-management approach to produce better cancer and overall health outcomes, said UNC Lineberger Comprehensive Cancer Center’s Samuel Cykert, MD. Credit: UNC Lineberger Comprehensive Cancer

Researchers at Children’s Hospital of Philadelphia (CHOP), St. Jude Children’s Research Hospital (St. Jude) and the Children’s Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (TLI) is pleased to announce that its WIC Program has received the U.S. Department of Agriculture’s Food and Nutrition Service (FNS) 2024 WIC Breastfeeding Gold Award of Excellence. The FNS notes that the “intent is

  Credit: Laura M. Lombardía / CNIO. “We have discovered a muscle-brain pathway that controls the eagerness to train more when we exercise,” explains Guadalupe Sabio, a researcher at the Spanish National Cancer Research Center (CNIO). One of the proteins identified activates the area of

The research was carried out in Dr. Johannes Karges’ Medicinal Inorganic Chemistry group in collaboration with doctoral student Nicolás Montesdeoca and two Bachelor students, Lukas Johannknecht and Elizaveta Efanova, and with the support of Dr. Jaqueline Heinen-Weiler from the Medical Imaging Center at Ruhr University

“This is the first report of spindle cell sarcoma BRAF V600E/S607T double-mutated, responding to a combination of B-Raf and MEK inhibitors.” Credit: 2024 Sinichenkova et al. “This is the first report of spindle cell sarcoma BRAF V600E/S607T double-mutated, responding to a combination of B-Raf and

This review offers an in-depth exploration of Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL), highlighting its distinct characteristics across various domains such as epidemiology, clinical presentation, histopathology, immunophenotype, genetic findings, and challenges in differential diagnosis. Credit: Elaine S. Jaffe, Yanna Ding This review offers an in-depth

Two studies published in the latest issue of the journal Cell by University of Pittsburgh researchers uncover how immunotherapies targeting the immune checkpoints PD1 and LAG3 work together to activate immune responses. The findings shed light on why combination therapies targeting both checkpoints can improve

A Rice University-led multi-institutional research collaboration has won an award of up to $18 million over five years from the Advanced Research Projects Agency for Health (ARPA-H) to develop and validate a new system for improving tumor removal accuracy for two types of cancer: breast,