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atr-inhibition-using-gartisertib-in-patient-derived-glioblastoma-cell-lines

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

“[…] this study identifies gartisertib as a potent ATRi within patient-derived glioblastoma cell lines.” Credit: 2024 Lozinski et al. “[…] this study identifies gartisertib as a potent ATRi within patient-derived glioblastoma cell lines.” BUFFALO, NY- January 17, 2024 – A new research paper was published
sars-cov-2-can-infect-dopamine-neurons-causing-senescence

SARS-CoV-2 can infect dopamine neurons causing senescence

A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers from Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Columbia University Vagelos
study-demonstrates-benefit-of-precision-medicine-based-on-race/ethnicity

Study demonstrates benefit of precision medicine based on race/ethnicity

“Precision medicine,” an emerging approach to health care in which a patient’s genetics, diseased tissue and other factors guide clinicians to personalize treatment strategies, can dramatically improve health outcomes for people with various diseases, notably cancer. Credit: Photo provided by the University of Oklahoma Health
nih-funded-uc-research-to-study-copper-effects-on-kidney-cancer

NIH-funded UC research to study copper effects on kidney cancer

Copper is an essential trace element required to produce energy in the body and allows humans to live in our atmosphere. But research has found that increased accumulation of copper is associated with worse outcomes for patients with the most common type of kidney cancer
a-new-targeted-treatment-calms-the-cytokine-storm

A new targeted treatment calms the cytokine storm

Osaka, Japan – Cytokines are chemical messengers that help the body get rid of invading bacteria and viruses, and control inflammation. The body carefully balances cytokines because they help keep the immune system healthy. However, this balance is upset if the immune system overreacts. A
tests-can-reveal-whether-an-antibody-can-turn-into-a-killer

Tests can reveal whether an antibody can turn into a killer

What makes a soldier switch sides? That is a really good question. Especially when the soldier is an antibody that is supposed to defend the body against one of the world’s most dangerous snake venoms but instead ends up helping the venom kill the body.
molecular-‘super-glue’-shows-promise-of-cancer-drug-discovery-platform

Molecular ‘super-glue’ shows promise of cancer drug discovery platform

(MEMPHIS, Tenn. – January 16, 2024) Today, St. Jude Children’s Research Hospital scientists published their work on SJ3149, a compound with broad activity against many cancer types, particularly acute myeloid leukemia (AML). SJ3149 sticks to the cancer-related protein casein kinase 1 alpha (CK1α), leading to
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