News

Copper is an essential trace element required to produce energy in the body and allows humans to live in our atmosphere. But research has found that increased accumulation of copper is associated with worse outcomes for patients with the most common type of kidney cancer

A team of melanoma researchers with the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) is honored with the 2023 Paper of the Year distinction by the Journal of Clinical Oncology. The recognition is for the results of the DREAMseq randomized phase 3 clinical trial. DREAMseq (EA6134) showed an

Osaka, Japan – Cytokines are chemical messengers that help the body get rid of invading bacteria and viruses, and control inflammation. The body carefully balances cytokines because they help keep the immune system healthy. However, this balance is upset if the immune system overreacts. A

What makes a soldier switch sides? That is a really good question. Especially when the soldier is an antibody that is supposed to defend the body against one of the world’s most dangerous snake venoms but instead ends up helping the venom kill the body.

(MEMPHIS, Tenn. – January 16, 2024) Today, St. Jude Children’s Research Hospital scientists published their work on SJ3149, a compound with broad activity against many cancer types, particularly acute myeloid leukemia (AML). SJ3149 sticks to the cancer-related protein casein kinase 1 alpha (CK1α), leading to

Australian scientists have pinpointed likely ‘cells-of-origin’, the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease. Credit: Must credit Dr Bianca Capaldo, WEHI Australian scientists have pinpointed likely ‘cells-of-origin’, the

About one hundred so-called cancer predisposition genes (CPGs) are known. The probability of developing cancer is greater in individuals who inherit certain altered variants of one of these genes. “But these 100 genes account for only about 10% of cancer cases. The vast majority of

T cell surface markers CD4 and LAG-3 are related proteins that promote and inhibit cell activity, respectively. However, although LAG-3 starts to be appreciated as an “immune checkpoint” molecule that can be targeted in cancer immunotherapy, only CD4 is well understood. Now, a comprehensive study

“Identification and validation of novel and targetable metabolic weaknesses in AML is ongoing.” Credit: 2023 Roma et al. “Identification and validation of novel and targetable metabolic weaknesses in AML is ongoing.” BUFFALO, NY- January 16, 2024 – A new editorial paper was published in Oncotarget’s

New study by Hebrew University reveals that a significant proportion (over one fifth) of human pluripotent stem cell samples that can be used in regenerative medicine possess cancer-related mutations, with the majority acquired during their propagation in culture. The findings underscore the importance of regular