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altered-brain-morphology-and-functional-connectivity-in-postmenopausal-women

Altered brain morphology and functional connectivity in postmenopausal women

“[…] our findings suggest that diminished brain volume and functional connectivity may be linked to menopause-related symptoms caused by the lower sex hormone levels.” Credit: 2024 Kim et al. “[…] our findings suggest that diminished brain volume and functional connectivity may be linked to menopause-related
unveiling-gender-differences-in-cancer:-new-insights-into-genomic-instability

Unveiling gender differences in cancer: new insights into genomic instability

Recent research spearheaded by Chunmei Cui at the State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, China, casts a new light on the nuanced interplay between gender and cancer, uncovering significant sex-specific disparities in copy number alterations (CNA) across various cancer types. Published
enhanced-melanoma-vaccine-offers-improved-survival-for-men

Enhanced melanoma vaccine offers improved survival for men

A second-generation melanoma vaccine being developed at UVA Cancer Center improves long-term survival for melanoma patients compared with the first-generation vaccine, new research shows. Interestingly, the benefit of the second-generation vaccine was greater for male patients than female patients. That finding could have important implications
study-flips-treatment-paradigm-in-bilateral-wilms-tumor,-shows-resistance-to-chemotherapy-may-point-toward-favorable-outcomes

Study flips treatment paradigm in bilateral Wilms tumor, shows resistance to chemotherapy may point toward favorable outcomes

(MEMPHIS, Tenn. – March 28, 2024) Resistance to chemotherapy is typically associated with poor outcomes for patients with cancer. However, St. Jude Children’s Research Hospital scientists demonstrated that in bilateral Wilms tumor (cancer in both kidneys) chemotherapy resistance can point toward a more favorable histology and an ultimatelygood outcome. The study revealed that tumors that do not respond to neoadjuvant, or tumor-shrinking, chemotherapy are predominantly composed of stromal
study-explores-the-future-of-at-home-cancer-treatment

Study explores the future of at-home cancer treatment

LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.    Credit: Ricardo Carrasco III LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility
journal-of-pharmaceutical-analysis-studies-find-promising-drug-candidates

Journal of Pharmaceutical Analysis studies find promising drug candidates

Understanding the underlying mechanisms of normal and pathological cellular processes is an essential during the process of drug discovery for identifying new therapeutic drug candidates. Fortunately, modern analytical techniques, coupled with well-established in vitro and in vivo experimental methodologies, has greatly accelerated progress on this
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