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Author: oncologs.com

periostin-shows-promise-to-help-fight-a-common-form-of-esophageal-cancer

Periostin shows promise to help fight a common form of esophageal cancer

Philadelphia, April 9, 2024 – Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia. New findings in The American Journal of Pathology, published by Elsevier, indicate that periostin, or POSTN, promotes ESCC progression by enhancing cancer and stromal
aacr:-how-cellular-plasticity-drives-cancer-metastasis

AACR: How cellular plasticity drives cancer metastasis

About 90% of deaths from cancer are a result of metastasis — that is, from cancer’s ability to spread from an initial primary tumor to seed new tumors throughout the body, often in the lungs, liver, and brain. Credit: Memorial Sloan Kettering Cancer Center About
study-reveals-mechanism-linking-heart-disease-to-cancer-development

Study reveals mechanism linking heart disease to cancer development

  Credit: Tel Aviv University   Previous studies have shown that heart disease and cancer may be connected through shared risk factors, such as smoking, diabetes, and obesity. However, a newly released study has shed light on the potential connection between extracellular bubbles released after
unlocking-the-body’s-hidden-weapon-against-cancer:-the-role-of-broken-chromosomes

Unlocking the body’s hidden weapon against cancer: the role of broken chromosomes

Scientists have unraveled the mechanisms of the Cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway activated by micronuclei, as well as its significant effects on tumor immunity. This study illuminates how chromosomal instability, marked by micronuclei formation, plays a critical role in
altered-brain-morphology-and-functional-connectivity-in-postmenopausal-women

Altered brain morphology and functional connectivity in postmenopausal women

“[…] our findings suggest that diminished brain volume and functional connectivity may be linked to menopause-related symptoms caused by the lower sex hormone levels.” Credit: 2024 Kim et al. “[…] our findings suggest that diminished brain volume and functional connectivity may be linked to menopause-related
unveiling-gender-differences-in-cancer:-new-insights-into-genomic-instability

Unveiling gender differences in cancer: new insights into genomic instability

Recent research spearheaded by Chunmei Cui at the State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, China, casts a new light on the nuanced interplay between gender and cancer, uncovering significant sex-specific disparities in copy number alterations (CNA) across various cancer types. Published
enhanced-melanoma-vaccine-offers-improved-survival-for-men

Enhanced melanoma vaccine offers improved survival for men

A second-generation melanoma vaccine being developed at UVA Cancer Center improves long-term survival for melanoma patients compared with the first-generation vaccine, new research shows. Interestingly, the benefit of the second-generation vaccine was greater for male patients than female patients. That finding could have important implications
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