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A second-generation melanoma vaccine being developed at UVA Cancer Center improves long-term survival for melanoma patients compared with the first-generation vaccine, new research shows. Interestingly, the benefit of the second-generation vaccine was greater for male patients than female patients. That finding could have important implications

Credit: Alexandra Fraik TAMPA, Fla. (March 28, 2024) – Over the past 30 years, Australia’s Tasmanian devil population has been afflicted with an infectious cancer that has pushed the species to near extinction. The marsupials are highly susceptible to devil facial tumor disease, which is almost

Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. During this phase a cell’s DNA is

(MEMPHIS, Tenn. – March 28, 2024) Resistance to chemotherapy is typically associated with poor outcomes for patients with cancer. However, St. Jude Children’s Research Hospital scientists demonstrated that in bilateral Wilms tumor (cancer in both kidneys) chemotherapy resistance can point toward a more favorable histology and an ultimatelygood outcome. The study revealed that tumors that do not respond to neoadjuvant, or tumor-shrinking, chemotherapy are predominantly composed of stromal

LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.    Credit: Ricardo Carrasco III LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility

Understanding the underlying mechanisms of normal and pathological cellular processes is an essential during the process of drug discovery for identifying new therapeutic drug candidates. Fortunately, modern analytical techniques, coupled with well-established in vitro and in vivo experimental methodologies, has greatly accelerated progress on this

UVA Health researchers have discovered a potential explanation for some of the most perplexing mysteries of COVID-19 and long COVID. The surprising findings could lead to new treatments for the difficult acute effects of COVID-19, long COVID and possibly other viruses. Credit: Dan Addison |

Cryoablation, a minimally invasive technique used to freeze and destroy small tumors, is effective for breast cancer patients with larger tumors, according to research presented by MSK interventional radiologist Yolanda Bryce, MD, at the 2024 Society of Interventional Radiology Annual Scientific Meeting. Credit: Memorial Sloan Kettering

Researchers at the University of Cambridge have created the world’s largest catalogue of human breast cells, which has revealed early cell changes in healthy carriers of BRCA1 and BRCA2 gene mutations. Credit: Sara Pensa/University of Cambridge Researchers at the University of Cambridge have created the

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer. Credit: Atsushi Saito, Hiroshima