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This review is designed by Professor Changyang Gong and written by his PhD student Shiyao Zhou. At the beginning, they elaborated the mechanism of CRISPR/Cas9 system. CRISPR/Cas9 system consists of Cas9 protein and single stranded directing RNA (sgRNA). In the presence of protospacer adjacent motif

NEW YORK, N.Y. and MEMPHIS, Tenn. February 1, 2024 – The Damon Runyon Cancer Research Foundation and St. Jude Children’s Research Hospital today announce the inaugural class of pediatric cancer research fellows. Each of the five fellows will receive funding for four years ($300,000 total)

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient. Credit: Jenny Hamilton, IGI/UC Berkeley Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic

The neurons that make up our brains and nervous systems mature slowly over many months. And while this may be beneficial from an evolutionary standpoint, the slow pace makes growing cells to study neurodegenerative and neurodevelopmental diseases — like Parkinson’s disease, Alzheimer’s disease, and autism

A multidisciplinary team of researchers that included 14 graduate students from The University of Texas at Arlington has created a new framework to provide optimal personalized treatment options for individuals with esophageal cancer. Credit: Photo courtesy UT Arlington A multidisciplinary team of researchers that included

Many cancer therapies, in addition to producing numerous side effects, fail to achieve complete tumour remission, partly due to the presence of cancer stem cells, which are difficult to eradicate. These cells can self-renew and play a key role in tumor recurrence and metastasis processes,

Having a high dietary intake of fish and vegetables at 1 year of age, and a low intake of sugar beverages, seems to protect against inflammatory bowel disease. These are the findings of a study with more than 80,000 children conducted at the University of

Following a national search, Tammy Mentzel, MPH, has been named executive director for center administration and associate director for administration at the University of Cincinnati Cancer Center. Mentzel has held this position in an interim capacity since February 2023. Credit: Photo/University of Cincinnati Following a

FOR IMMEDIATE RELEASE Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & Graphics FOR IMMEDIATE RELEASE A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) — soft tissue tumors that are stubbornly resistant to chemotherapy and radiation —

In a rare but serious complication of cancer, the body’s own immune system can start attacking the brain, causing rapid-onset memory loss and cognitive deficits. What triggers this sudden biological civil war was largely unknown. Credit: Junjie Xu In a rare but serious complication of